What is Serotonin?


Başak Arya Gençler

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Hey guys, nice to see you again! “What is Dopamine?” I published an article entitled. This week, I’m going to talk about the hormone Serotonin, which is considered his brother and works pretty well together.

Serotonin is created by a biochemical conversion process that combines tryptophan, a component of proteins, with tryptophan hydroxylase, a chemical reactor. Together, they form 5-hydroxytryptamine (5-HT), or serotonin


Serotonin is most commonly believed to be a neurotransmitter, although some consider it to be a hormone. It is produced in the intestines and the brain. It is also present in the blood platelets and the central nervous system (CNS).

As it occurs widely throughout the body, it is believed to influence a variety of body and psychological functions.

Serotonin cannot cross the blood-brain barrier, so any serotonin that is used inside the brain must be produced inside the brain.

Serotonin deficiency symptoms

Low levels of serotonin have been linked with:

  • poor memory
  • low mood
    They may also lead to the following symptoms:
  • craving for sweet or starchy foods
  • difficulty sleeping
  • low self-esteem
  • anxiety
  • aggression


The Role of Serotonin in Brain Function

In addition to depression, serotonin may play a role in other brain and mental health disorders, including anxiety disorder, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), phobias, and even epilepsy.

Serotonin plays an important role in many other body functions, too. It’s involved in appetite and digestion (bowel function and bowel movements), bone health, sex, and sleep.

Serotonin is a precursor to melatonin, a chemical that helps regulate the body’s sleep-wake cycle. Certain antidepressants that raise serotonin levels have been associated with sexual dysfunction.

Too high or too low levels of serotonin have been linked to diseases such as irritable bowel syndrome (IBS), heart disease, and osteoporosis -a disease that weakens the bones -according to an article published in April 2016 in the journal Cell.

Selective Serotonin Reuptake Inhibitors (SSRIs)

Selective serotonin reuptake inhibitors, or SSRIs, are a class of drugs used to treat depression and anxiety. They’re the most popular class of antidepressants. (5)

Commonly prescribed SSRIs include:

  • Citalopram (Celexa)
  • Escitalopram (Lexapro)
  • Fluoxetine (Prozac)
  • Paroxetine (Paxil, Pexeva)
  • Sertraline (Zoloft)
  • Vilazodone (Viibryd)How Do SSRI Drugs Work?SSRIs are thought to work by increasing serotonin levels in the brain. SSRIs do this by blocking the absorption of serotonin by nerve cells, keeping more of it available for passing along further messages between nerve cells in the brain.Other groups of antidepressants, called serotonin and norepinephrine reuptake inhibitors (SNRIs) and serotonin-norepinephrine-dopamine reuptake inhibitors (SNDRIs), block the absorption of serotonin and the other neurotransmitters norepinephrine and dopamine.

    SSRIs are sometimes called second generation antidepressants. In general, these antidepressants have fewer side effects than older tricyclic antidepressants.

    Still, there are still several common side effects associated with SSRI use. These may include:

  • Dry mouth
  • Nausea
  • Insomnia
  • Headache
  • Nervousness (jitters)
  • Weight gain
  • Diarrhea
  • Sweating
  • Sexual dysfunctionSome people -especially children, teens, and young adults – may have an increase in suicidal thoughts while taking SSRIs.
  • These side effects are most common when people first start to take SSRIs -or when they change a dose – and tend to lessen over time.
  • In short, be happy. There’s no reason why you shouldn’t be happy. You can be grateful that you can start a new day. You can be grateful that you can read this article right now, or that you have equipment that can access this article. If you can breathe unaided and walk around waving your hand, you can be grateful. If your family is with you, if you can go to school and do a lot more, you have a lot to be thankful for.Take care, stay healty, stay yourself.
    Hope see you again, bye!
    Başak Arya Gençler
  • https://www.medicalnewstoday.com/articles/232248
  • https://www.everydayhealth.com/serotonin/guide/